Table 3 Association of SCIN items and relevant variables by ordinal Logistic Regression analysis
Age (OR for decadal steps) | Cisplatin (OR for steps of 100 mg/m2) | GSTM1 (+ vs.- as Reference) | GSTT1 (+ vs.- as Reference) | GSTP1 (GG vs. AA/AG as Reference) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
P | OR (95%CI)* | P | OR (95% CI)* | P | OR (95% CI)* | P | OR | P | OR (95% CI)* | |
Paresthesias fingers | 0.046 | 1.29 (1.01–1.67) | 0.178 | 1.11 (0.95–1.29) | 0.057 | 1.68 (0.98–2.76) | 0.926 | 1.03 | 0.039 | 0.46 (0.22–0.96) |
Paresthesias toes | <0.001 | 1.82 (1.40–2.37) | <0.001 | 1.34 (1.14–1.57) | 0.050 | 1.68 (1.00–2.81) | 0.704 | 0.88 | 0.023 | 0.42 (0.20–0.88) |
Raynaud's P. fingers | 0.058 | 1.27 (0.99–1.62) | 0.021 | 1.27 (1.03–1.39) | 0.235 | 1.35 | 0.944 | 0.98 | 0.920 | 0.97 |
Raynaud's P. toes | 0.022 | 1.34 (1.04–1.72) | <0.001 | 1.33 (1.14–1.56) | 0.072 | 1.60 (0.96–2.66) | 0.355 | 0.73 | 0.052 | 0.49 (0.24–1.01) |
Tinnitus | 0.153 | 1.20 | 0.001 | 1.32 (1.12–1.55) | 0.962 | 1.01 | 0.107 | 1.83 | 0.008 | 0.33 (0.14–0.74) |
Hearing Impairment | <0.001 | 1.61 (1.24–2.09) | <0.001 | 1.34 (1.14–1.56) | 0.025 | 1.81 (1.08–3.03) | 0.595 | 1.20 | 0.553 | 0.81 |