Table 1 aPTT coagulation time of normal plasma and Leiden plasma (100 μL) with and without incubation for 5 minutes with peptide 1–16 or NaCl as control.
From: SV-IV Peptide1–16 reduces coagulant power in normal Factor V and Factor V Leiden
Plasmas incubated with peptide 1–16 | aPTT coagulation time (sec.) | Plasmas incubated with NaCl | aPTT coagulation time (sec.) | p |
|---|---|---|---|---|
Normal plasma incubated at T0 with peptide 1–16 | 40 ± 5 | Normal plasma incubated at T0 with NaCl | 38 ± 3 | 0,16 |
Leiden plasma incubated at T0 with peptide 1–16 | 41 ± 4 | Leiden plasma incubated at T0 with NaCl | 40 ± 4 | 0,59 |
Normal plasma incubated with peptide 1–16 at T1 | 90 ± 6 | Normal plasma incubated at T1 with NaCl | 37 ± 4 | 0,000 |
Leiden plasma incubated at T1 with peptide 1–16 | 120 ± 9 | Leiden plasma incubated at T1 with NaCl | 38 ± 3 | 0,000 |