Figure 2

Activity of different NO donors. all the cancer cell lines were exposed for 24 hours to NCX 4040 ■, NONOATE □, SNP ▲, SNAP O, at concentrations of 1, 5, 10 and 50 μM, followed by a 24-hour wash-out. Growth inhibition and cytocidal effect of drugs were calculated according to Monks' formula, as reported in Materials and methods. Each point indicates the mean of at least three experiments; SD never exceeded 5%.