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Table 1 Summary of clinical parameters

From: Mycobacterium avium complex immune reconstitution inflammatory syndrome: Long term outcomes

Characteristic

Responders N = 16

Non-responders N = 4

Age

40

38

Ethnicity:

  

   Caucasian

8

3

   African-American

7

1

   Hispanic

1

0

Gender (male)

13

4

MAC prophylaxis

4

3

Prior disseminated MAC

4

4

Time to IRIS (mean)

248 days

195 days

IRIS site*:

  

   Lymph node(s)

11

4

   GI tract

5

2

   Liver

3

0

IRIS therapy†:

  

   2 drugs

8

2

   3 drugs

6

0

   4 or more drugs

2

2

Time to resolution or follow up (mean)

522 days

888 days

  1. * Patients may have had more than one site of IRIS involvement.
  2. †2 drugs – macrolide + ethambutol, 3 drugs – addition of rifabutin, 4 or more drugs – addition of amikacin, fluoroquinolone, or linezolid.