Table 1 Genes over-expressed in spleen of Immune Mice. Values within square brackets [] represent the fold increase in the expression of each gene by mice vaccinated with semi-allogeneic vaccines compared to mice mock-vaccinated with PBS.

CD80 (B7-1) [1.9]

CD86 (B7-2) [1.8]

Cell surface molecules expressed by activated APC that provide a co-stimulatory signal to T cells by interacting with CD28

C2ta [2.0]

Enhancer of T-cell activation and proliferation and suppressor of Th2-type cytokine expression

STAT1 [2.0]

Signal transducer and activator of transcription 1, activated by various ligands including interferon α (IFN- α) and IFN-γ

STAT4 [2.0]

Another member of the Stat family of transcription factors that is essential for mediating responses to IL-12 in lymphocytes and for regulating the differentiation of T helper cells

CD40 [2.0]

A co-stimulatory molecule expressed on the surface of B lymphocytes, dendritic cells, and follicular dendritic cells

FASLG [1.8]

Critical for triggering apoptosis of some types of cells following interaction with FAS

HAVCR2 [2.5]

Hepatitis A virus cellular receptor 2, over-expressed by activated CD4 Th1 cells and CD11b+ macrophages