Table 5 Comparison of the most common (frequency > 2%) HLA-A/B, Cw/B and A/Cw two-loci haplotypes in Tunisians, Tunisian NPC patients and in ME

A/B

A*020101 B*5001

0.045

2.20

0.20

8.9

< 0.01

0.044

2.70

0.33

16

< 0.001

0.029

3.50

NS

A*020101 B*440201

0.037

2.90

0.74

40.0

< 0.001

Not present

0.022

0.24

NS

A*2301 B*5001

0.030

2.00

0.29

14.0

< 0.001

(0.011)

Not present

A*6802 B*1402

0.023

2.00

0.41

49.0

< 0.001

Not present

(0.015)

A*020101 B*510101

0.020

1.10

0.25

5.1

< 0.05

(0.018)

(0.015)

A*010101 B*570101

(0.003)

0.022

1.80

0.62

23

< 0.001

(0.015)

A*020101 B*180101

(0.010)

0.030

1.80

0.33

10

< 0.01

0.022

NS

A*020101 B*440301

(0.013)

0.033

1.80

0.24

7.6

< 0.01

0.029

NS

A*2902 B*440301

(0.012)

0.021

1.60

0.29

15

< 0.001

Not present

A*3402 B*0801

(0.006)

0.022

2.00

0.72

58

< 0.001

Not present

Cw/B

Cw*0701 B*0801

0.047

3.90

0.70

68.00

< 0.001

0.056

4.40

0.75

58

< 0.001

0.089

55.97

< 0.001

Cw*040101 B*4403

(0.016)

0.047

3.50

0.45

36

< 0.001

0.081

31.17

< 0.001

Cw*0602 B*5001

0.120

9.10

0.84

120.00

< 0.001

0.081

6.20

0.77

76

< 0.001

0.073

42.62

< 0.001

Cw*1701,03 B*4102

0.020

1.90

1.00

120.00

< 0.001

0.026

2.50

1.00

160

< 0.001

0.065

124.00

< 0.001

Cw*0701 B*4901

0.027

2.30

1.00

57.00

< 0.001

0.041

3.40

0.99

57

< 0.001

0.056

34.40

< 0.001

Cw*0802 B*1402

0.037

3.40

0.67

130.00

< 0.001

(0.007)

0.040

87.08

< 0.001

Cw*040101 B*3501

0.020

1.70

0.71

30.00

< 0.001

Not present

0.040

30.68

< 0.001

Cw*0501 B*4402

0.040

3.80

0.85

22.00

< 0.001

(0.018)

1.70

0.53

61

< 0.001

0.040

25.79

< 0.001

Cw*0501 B*1801

Not present

0.022

2.00

0.52

43

< 0.001

0.032

36.37

< 0.001

Cw*0602 B*4501

0.033

2.30

0.64

22.00

< 0.001

(0.011)

0.81

0.67

7.8

< 0.01

0.032

13.03

< 0.001

Cw*0702 B*070201

0.033

3.10

0.82

150.00

< 0.001

(0.018)

1.80

0.97

130

< 0.001

0.025

92.21

< 0.001

Cw*0202 B*440301

0.027

2.20

0.33

34.00

< 0.001

(0.012)

0.032

NS

Cw*1502 B*510101

0.033

3.20

1.00

180.00

< 0.001

0.044

4.10

1.00

140

< 0.001

(0.016)

Cw*1601 B*440301

0.027

2.40

0.59

62.00

< 0.001

0.022

1.90

0.51

30

< 0.001

(0.008)

Cw*1202 B*520101

0.023

2.30

1.00

30.00

< 0.001

0.030

2.90

0.89

220

< 0.001

Not present

Cw*040101 B*5301

0.020

1.70

0.83

35.00

< 0.001

0.037

3.20

1.00

68

< 0.001

(0.008)

Cw*120301 B*3801

0.020

1.90

1.00

140.00

< 0.001

(0.018)

Not present

Cw*0602 B*1302

(0.017)

0.026

2.10

1.00

30

< 0.001

Not present

Cw*020204 B*1503

(0.014)

0.033

3.20

1.00

280

< 0.001

(0.016)

Cw*0701 B*180101

Not present

0.037

2.60

0.46

21

< 0.001

(0.008)

Cw*0602 B*570101

(0.003)

0.033

2.70

1.00

40

< 0.001

(0.008)

A/Cw

A*020101 Cw*0602

0.061

2.40

0.18

7.60

< 0.01

0.023

NS

0.077

11.00

< 0.001

A*030101 Cw*0602

0.035

2.10

0.40

12.00

< 0.001

0.033

1.90

0.32

9.4

< 0.01

Not present

A*010101 Cw*040101

0.033

2.20

0.29

17.00

< 0.001

(0.007)

Not present

A*020101 Cw*0501,03

0.032

2.40

0.63

28.00

< 0.001

0.022

1.50

0.46

12

< 0.001

(0.012)

A*2301 Cw*0602

0.032

1.60

0.27

6.50

< 0.05

(0.016)

Not present

A*010101 Cw*0602

Not present

0.041

1.60

0.15

3.9

NS

0.026

NS

A*010101 Cw*0701

0.023

NS

0.037

1.60

0.14

4.2

NS

(0.016)

A*020101 Cw*040101

(0.014)

0.037

1.40

0.13

3.3

NS

0.040

NS

A*020101 Cw*0701

0.023

NS

0.036

NS

0.020

NS

A*2902 Cw*1601

(0.010)

0.022

1.90

0.52

48

< 0.001

Not present

A*3402 Cw*0701

(0.007)

0.022

1.70

0.69

20

< 0.001

(0.016)