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Table 1 HLA-A, -B and -Cw allele frequencies in ME and TU

From: Associations between HLA Class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians

HLA-A allele (ME n = 73; TU n = 147)
  ME TU   ME TU   ME TU
A*010101 0.137 0.088 A*110101 0.048 0.030 A*3301 0.055 0.031
A*0102 0 0.003 A*2301 0.082 0.078 A*3303 0 0.01
A*0103 0 0.007 A*240201 0.062 0.037 A*33new* 0 0.003
A*020101 0.178 0.173 A*250101 0.007 0.007 A*3402 0.021 0.01
A*0202 0 0.034 A*2601 0.007 0.031 A*3601 0 0.003
A*0205 0 0.024 A*2902 0.041 0.061 A*6601 0.021 0.02
A*0212 0 0.003 A*3001 0.014 0.031 A*680101 0.021 0.031
A*0285 0 0.003 A*3002 0.089 0.044 A*680102 0.021 0.014
A*02new* 0 0.003 A*3004 0.007 0.003 A*680201 0.048 0.054
A*030101 0.034 0.068 A*3010 0 0.003 A*7401 0.014 0.003
A*030103 0 0.003 A*310102 0.021 0.024 A*8001 0 0.007
A*0302 0.041 0.017 A*3201 0.034 0.034    
HLA-B allele (ME n = 69; TU n = 148)         
  ME TU   ME TU   ME TU
B*070201 0.022 0.041 B*3508 0 0.014 B*4901 0.051 0.027
B*0705,06 0.007 0.003 B*3701 0.007 0.007 B*5001 0.073 0.139
B*0801** 0.087 0.064 B*3801 0.014 0.020 B*5002 0.043 0.014
B*1302°° 0 0.017 B*390602 0 0.003 B*510101,02 0.043 0.054
B*1401 0.014 0.010 B*3910 0.007 0.007 B*5108 0 0.003
B*1402 0.036 0.054 B*3920 0 0.003 B*520101,02 0.007 0.024
B*1403 0 0.010 B*4001 0 0.010 B*5301^^ 0.014 0.024
B*150101 0 0.014 B*4002 0.007 0.003 B*5303 0 0.003
B*1503 0.014 0.017 B*4101 0 0.017 B*53new* 0 0.003
B*1510 0 0.004 B*4102 0.065 0.020 B*5501 0 0.003
B*1516 0 0.017 B*4201 0 0.017 B*570101 0.014 0.003
B*151701 0 0.007 B*4202 0.007 0.007 B*5702 0 0.003
B*180101 0.051 0.023 B*4402 0.094 0.047 B*570302 0.007 0
B*2702 0.007 0.007 B*440301 0.116 0.071 B*5801 0.014 0.027
B*2703 0.007 0 B*440302 0.007 0 B*5802 0.007 0.003
B*2705,13^ 0.021 0.010 B*4405 0 0.003 B*7301 0 0.007
B*350101,42 0.043 0.027 B*4427 0 0.007 B*7801 0.014 0
B*3502 0.007 0.017 B*4501 0.043 0.047    
B*3503 0.014 0.014 B*470101 0.007 0.003    
HLA-Cw allele (ME n = 63; TU n = 147)         
  ME TU   ME TU   ME TU
Cw*0102 0 0.007 Cw*0602 0.183 0.218 Cw*140201 0.008 0.027
Cw*020202*** 0.095 0.054 Cw*0701,06° 0.183 0.129 Cw*150201 0.016 0.034
Cw*0210 0.016 0.017 Cw*070201 0.032 0.054 Cw*150501,02 0.016 0.014
Cw*0302 0 0.010 Cw*0704,0711 0.016 0.010 Cw*1601 0.032 0.044
Cw*030301 0 0.003 Cw*0802 0.056 0.058 Cw*1602 0.016 0.007
Cw*030401, 02°°° 0 0.014 Cw*120201,02 0.008 0.024 Cw*160401 0 0.003
Cw*040101 0.159 0.126 Cw*120301 0.008 0.044 Cw*1701,02,03^^^ 0.071 0.051
Cw*0501,03 0.087 0.048 Cw*12new* 0 0.003    
  1. Alleles having a frequency > 5% are in bold. °Including Cw*070101,02; **Two samples in this group were assigned as B*080101; °°One sample in this group was assigned as B*130201; ^Two samples in this group were assigned as B*270502 (1ME, 1TU); ^^Two samples in this group were assigned as B*530101; ***One sample in this group was assigned as Cw*0202; °°°One sample in this group was assigned as Cw*0304; ^^^Cw*1703, af = 0.063 in ME.
  2. Not discriminated alleles due to polymorphisms outside the assayed exons are listed separated by ",". Nomenclature was updated until the sixth digit; seventh and eighth digits were not included in the table. In case of ambiguous allele combinations, the most frequent allele combination was included in the analysis.
  3. No statistically significant differences were identified in any comparison between the Tunisian and Moroccan cases.
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Journal of Translational Medicine

ISSN: 1479-5876

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