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Table 3 Genes that positively correlate with NEP

From: Clinical relevance of Neutral Endopeptidase (NEP/CD10) in melanoma

Gene Probe

Gene Symbol

corA*

corB**

p-value***

Gene Name

208469_s_at

EGFL8

0.819

0.852

0.00006

EGF-like-domain, multiple 8

209826_at

PPT2

0.729

0.861

0.00008

palmitoyl-protein thioesterase 2

226270_at

EXOC2

0.659

0.751

0.00006

exocyst complex component 2

201537_s_at

DUSP3

0.632

0.79

0.00006

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

223057_s_at

XPO5

0.665

0.706

0.00018

exportin 5

209238_at

STX3A

0.729

0.747

0.00048

syntaxin 3A

200824_at

GSTP1

0.729

0.765

0.00086

glutathione S-transferase pi

208899_x_at

ATP6V1D

0.618

0.673

0.00035

ATPase, H+ transporting, lysosomal 34 kDa, V1 subunit D

223113_at

HSPC196

0.718

0.765

0.00135

NA

209490_s_at

PPT2

0.514

0.737

0.00012

palmitoyl-protein thioesterase 2

200692_s_at

HSPA9B

0.557

0.667

0.00035

heat shock 70 kDa protein 9B (mortalin-2)

223056_s_at

XPO5

0.527

0.738

0.00048

exportin 5

202475_at

NIFIE14

0.514

0.781

0.00035

NA

227124_at

NA

0.665

0.753

0.00147

NA

203723_at

ITPKB

0.718

0.646

0.00086

inositol 1,4,5-trisphosphate 3-kinase B

200924_s_at

SLC3A2

0.527

0.697

0.0009

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

211968_s_at

HSP90AA1

0.43

0.831

0.00006

heat shock protein 90 kDa alpha (cytosolic), class A member 1

219526_at

C14orf169

0.49

0.615

0.00035

chromosome 14 open reading frame 169

218465_at

TMEM33

0.729

0.697

0.00307

transmembrane protein 33

200691_s_at

HSPA9B

0.632

0.653

0.00243

heat shock 70 kDa protein 9B (mortalin-2)

212793_at

DAAM2

0.618

0.566

0.00064

dishevelled associated activator of morphogenesis 2

201089_at

ATP6V1B2

0.618

0.601

0.0019

ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B2

218305_at

IPO4

0.43

0.683

0.00035

importin 4

32836_at

AGPAT1

0.618

0.56

0.00113

1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

201195_s_at

SLC7A5

0.43

0.642

0.00048

solute carrier family 7 (cationic amino acid transporter, y+ system), member 5

202088_at

SLC39A6

0.418

0.825

0.00064

solute carrier family 39 (zinc transporter), member 6

205512_s_at

PDCD8

0.527

0.604

0.00307

programmed cell death 8 (apoptosis-inducing factor)

1554679_a_at

LAPTM4B

0.665

0.545

0.0019

lysosomal associated protein transmembrane 4 beta

226101_at

PRKCE

0.514

0.542

0.00064

protein kinase C, epsilon

214359_s_at

HSP90AB1

0.402

0.651

0.00035

heat shock protein 90 kDa alpha (cytosolic), class B member 1

239406_at

ZNF193

0.49

0.642

0.00387

zinc finger protein 193

204015_s_at

DUSP4

0.665

0.6

0.00483

dual specificity phosphatase 4

201771_at

SCAMP3

0.43

0.583

0.00147

secretory carrier membrane protein 3

203914_x_at

HPGD

0.618

0.561

0.00483

hydroxyprostaglandin dehydrogenase 15-(NAD)

211373_s_at

PSEN2

0.43

0.542

0.0019

presenilin 2 (Alzheimer disease 4)

220272_at

BNC2

0.659

0.575

0.00736

basonuclin 2

  1. *corA = calculated correlation dichotomized based on ratio to lymph node
  2. **corB = Pearson correlation
  3. ***p-value for w-stat: p-value for Wilcoxan rank-sum test