Skip to main content

Table 2 Characteristics of primary DCs following maturation with different cocktails

From: Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70

Parameter   DC1 DC2 DC3 DC4 DC5
Recovery (% seeded cells) N* 4 4 3 2 2
  m+ 32.8 17.6 19.0 17.9 18.1
  std# 18.7 9.2 5.5 3.0 6.0
Recovery (% CD14+cells) N* 4 4 3 3 2
  m+ 42.6 22.2 25.4 24.0 25.5
  std# 22.0 9.7 6.2 2.8 3.1
% viable cells (7AAD-neg cells) N* 5 5 4 5 3
  m+ 97.5 88.9 96.0 96.0 94.0
  std# 0.9 3.7 1.6 1.2 1.4
% CD14+cells N* 5 5 4 5 3
  m+ 2.2 2.5 1.6 2.5 3.1
  std# 2.2 3.0 0.9 3.1 4.1
% CD83+ cells N* 5 5 4 5 3
  m+ 94.2 82.3 95.1 90.6 92.4
  std# 3.0 7.1 2.3 10.7 1.7
% CCR7+ cells N* 5 5 4 5 3
  m+ 79.7 67.5 75.2 74.4 85.2
  std# 7.2 5.6 8.7 11.8 0.7
% CD80+ cells N* 5 5 4 5 3
  m+ 80.7 70.8 83.2 85.5 85.3
  std# 12.5 10.9 10.7 8.9 11.0
% CD86+ cells N* 5 5 4 5 3
  m+ 95.1 89.6 94.2 94.7 95.8
  std# 2.2 4.5 2.2 2.1 0.8
  1. * N = number of independent donors
  2. + m = mean
  3. #std = standard deviation