From: Tumor-specific T cells signal tumor destruction via the lymphotoxin β receptor
Adoptive immunotherapy a | Mean number of pulmonary metastases b | ||||
---|---|---|---|---|---|
Donor | Hosts | Number of T cells transferred | Blocking proteinsb | Exp.1 | Exp.2 |
None | wt | 0 | none | 250 | 250 |
LKO | wt | 15 | rat IgG | 0 d | 81(35)d |
LKO | wt | 15 | Anti-IFN-γ | 39(29)d | 242(8)e |