Figure 3
Detection of tet572-positive CD8 T lymphocytes after booster vaccination with transgenic B lymphocytes. (A). Tet572-positive CD8 T cell responses, ex vivo and after in vitro peptide restimulation, in patient #112 of cohort 4a who received two injections of transgenic freshly prepared lymphocytes at the dose of 0.5 × 105 each one month apart. (B). Detection of tet572-positive CD8 T cell responses, ex vivo and after in vitro peptide restimulation, in patient #115 of cohort 4b who received an injection of freshly prepared transgenic B lymphocytes at the dose of 0.5 × 105 followed one month later by a similar dose of transgenic lymphocytes.