The thrombopoietin receptor, c-Mpl, is a selective surface marker for human hematopoietic stem cells

Table 2 Repeated Measures Two-way ANOVA of c-mpl expression in Human HSC/PC: Stage vs. Tissue Source

	Stage	Tissue	Interaction	Bonferroni's Multiple Comparison			Linear Trend (One-way)
% c-mpl+	<0.0001	0.8918	0.2949	Stage I vs. II	Stage II vs. III	Stage III vs. IV	Order: I-II-III-IV
FL			FL	<0.01	<0.001	NS	<0.0001
UCB			UCB	<0.05	<0.001	NS	<0.0001
ABM			ABM	<0.05	<0.001	NS	<0.0001
mPBSC			mPBSC	<0.01	<0.001	NS	<0.0001
c-mpl *RMFI*	<0.0001	0.2102	0.0779	Stage I vs. II	Stage II vs. III	Stage III vs. IV	Order: I-II-III-IV
FL			FL	NS	<0.05	NS	<0.0001
UCB			UCB	NS	<0.01	NS	<0.001
ABM			ABM	NS	<0.001	NS	<0.0001
mPBSC			mPBSC	<0.01	<0.001	NS	<0.0001

Values represent calculated p values for the indicated analyses. ABM, adult bone marrow; ANOVA, analysis of variance; FL, fetal liver; HSC/PC, hematopoietic stem cells/progenitor cells; mPBSC, cytokine-mobilized peripheral blood stem cells; NS, not significant (p > 0.05); RMFI, relative median fluorescence intensity; UCB, umbilical cord blood

ISSN: 1479-5876