Figure 1
From: In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer
Immunohistochemical labeling of CD8+ and CD3+/FOXP3+ T cells of representative colon cancer specimens with one case demonstrating a high number of CD8+ T cells (A) and CD3+ T cells (red, membranous) with a high proportion of regulatory T cells co-expressing FOXP3 (brown, nuclear) in the stroma (C) and the malignant epithelium of the tumor (inset) and another case with a low number of CD8+ T cells (B) and only a few CD3+ T cells and FOXP3+ Treg (D).