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Table 4 Factors Whose Levels Differed Between Heat Inactivated Plasma and Plasma

From: Comparison of proteomic profiles of serum, plasma, and modified media supplements used for cell culture and expansion

  Factor Levels   
Factor Plasma Heat Inactivated Plasma Fold Difference p*
Factors whose levels were greater in heat inactivated plasma
MPO (pg/mL) 359 ± 245 2,703 ± 1,171 9.29 ± 4.56 5.42E-07
Eotaxin 2 (pg/mL) 989 ± 576 2,352 ± 1,376 2.57 ± 1.04 0.00012
MCP-1 (pg/mL) 361 ± 97 425 ± 111 1.18 ± 0.10 0.00014
PAI-1 total (pg/mL) 929 ± 745 1,709 ± 183 1.62 ± 0.59 0.0026
TNFR1 (pg/mL) 422 ± 103 499 ± 116 1.19 ± 0.20 0.0093
Factors whose levels were greater in plasma
MIP-1α (pg/mL) 56.4 ± 8.8 0.0 ± 0 NA 2.76E-14
Ang 2 (pg/mL) 212 ± 95.2 0.0 ± 0 NA 8.61E-11
MDC (pg/mL) 350 ± 70.6 219.7 ± 36.3 1.58 ± 0.13 2.16E-08
IL-6R (ng/mL) 13.2 ± 4.45 0.043 ± 0.072 307 ± 563 6.67E-08
SDF-1β (pg/mL) 798 ± 137 336 ± 95.7 2.46 ± 0.47 1.86E-07
MMP-10 (pg/mL) 291 ± 183 3.3 ± 10.3 88.2 ± 10.2 2.03E-07
VCAM (ng/mL) 556 ± 133 113 ± 43.4 5.44 ± 2.23 5.36E-07
Fibrinogen (microg/mL) 4,812 ± 1,779 0.107 ± 0.300 45,029 ± 23,528 1.16E-06
PAI-1active (pg/mL) 4,192 ± 4,600 67.9 ± 89.0 61.7 ± 14.5 2.02E-06
MMP-2 (ng/mL) 114 ± 8.4 34.1 ± 21.4 4.01 ± 1.62 7.45E-06
ICAM-1 (ng/mL) 321 ± 37.9 201 ± 242 1.62 ± 0.3 1.33E-05
CRP (ng/mL) 1,749 ± 1,732 729 ± 921 2.75 ± 0.97 1.99E-05
MPIF-1 (pg/mL) 1,618 ± 368 483 ± 214 4.26 ± 3.18 2.12E-05
PDGF-BB (pg/mL) 32.7 ± 19.8 7.3 ± 17.7 4.48 ± 1.65 4.44E-05
MIP-3β (pg/mL) 88.2 ± 22.4 43.6 ± 11.7 2.11 ± 0.67 4.65E-05
MIP-3α (pg/mL) 11.8 ± 6.3 2.3 ± 2.1 5.13 ± 1.51 6.24E-05
ITAC (pg/mL) 51.0 ± 7.3 17.6 ± 9.9 3.78 ± 1.88 6.84E-05
MMP-3 (ng/mL) 13.86 ± 4.42 660 ± 610 20.99 ± 50.6 0.00057
RANTES (ng/mL) 5.77 ± 2.22 4.19 ± 1.76 1.42 ± 0.32 0.00066
MIP-1β (pg/mL) 74.3 ± 58.6 53.4 ± 36.0 1.38 ± 0.26 0.00087
HGF (pg/mL) 532 ± 159 353 ± 160 1.65 ± 0.48 0.00098
NAP-2 (ng/mL) 184 ± 321 152 ± 280 1.28 ± 0.23 0.0011
Lymphotactin (pg/mL) 103.1 ± 95.7 64.8 ± 66.6 2.11 ± 0.99 0.0013
G-CSF (pg/mL) 65.4 ± 46.6 24.7 ± 38.2 2.65 ± 3.80 0.0016
IL-16 (pg/mL) 711 ± 573 327 ± 447 5.66 ± 6.47 0.0018
Leptin (ng/mL) 9.23 ± 12.33 1.12 ± 1.24 8.25 ± 5.07 0.0023
TARC (pg/mL) 41.4 ± 11.8 34.5 ± 11.7 1.23 ± 0.20 0.0025
MMP-1 (pg/mL) 1,170 ± 636 248 ± 301 4.72 ± 2.13 0.0045
L-Selectin (microg/mL) 1.99 ± 0.32 1.71 ± 0.20 1.16 ± 0.14 0.0049
TNFR2 (pg/mL) 434 ± 74 295 ± 104 1.63 ± 0.68 0.0051
Eotaxin 2 (pg/mL) 104 ± 49 67.7 ± 40.7 1.94 ± 1.26 0.0099
  1. *p values were calculated using Student's paired T tests and natural log transformed data.
  2. Values are mean ± one standard deviation.