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Figure 6 | Journal of Translational Medicine

Figure 6

From: Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma

Figure 6

Functional potential of patients' dendritic cells and T cells. (A) Proliferation of allogeneic T cells (pooled in equal amounts from four healthy donors) stimulated by MDCs from Patient 1–6 (full symbols) and normal MDCs (open symbols); (B) Proliferation of patients' T cells (full symbols) and normal T cells (open symbols) in response to stimulation by normal allogeneic MDCs pooled in equal amounts from four normal donors; (C) Interferon-γ secretion by patients' T cells (full symbols) and normal T cells (open symbols) upon stimulation by autologous MDCs previously pulsed with an influenza vaccine in vitro. Horizontal lines stand for mean values (longer lines) ± standard deviation.

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