Figure 1

Antitumor effects of XPE. XPE preparations were dissolved into sterile, injection-grade PBS at a concentration of 2 mg/ml, and injections of 50 uL (total mass 10 ug) were performed subcutaneously into C57/BL6 mice 7 days before tumor challenge. 5 × 10⁵ B16 murine melanoma cells were injected subcutaneously into the hind limb flank of female 6–8 week-old C57BL/6. Tumor growth was assessed every 3 days by two measurements of perpendicular diameters by a caliper, and animals were sacrificed when tumors reached a size of 1 cm in any direction. *p < 0.05, Student's T test compared to saline treated.