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Table 1 Apoptotic cells after a 24- or 48-h exposure to various concentrations of NCX 4040

From: In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines

Cell Line 24 h 48 h
5 μM 10 μM 50 μM 5 μM 10 μM 50 μM
LoVo Dx 0.7 ± 0.01 0.5 ± 0.01 0.5 ± 0.02 0.5 ± 0.0 0.02 ± 0.01 0.2 ± 0.0
WiDr 1.0 ± 0.01 4.0 ± 0.1 1.0 ± 0.05 2.0 ± 0.03 5.0 ± 0.02 5.0 ± 0.03
LRWZ 3.0 ± 0.03 5.0 ± 0.02 4.0 ± 0.1 4.0 ± 0.01 21.0 ± 0.3 60.0 ± 1.3
LoVo 2.0 ± 0.05 90.0 ± 2.3 n.e.* 3.0 ± 0.02 n.e. n.e.
  1. * n.e.: not evaluated