Table 1 Apoptotic cells after a 24- or 48-h exposure to various concentrations of NCX 4040
From: In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines
Cell Line | 24 h | 48 h | ||||
|---|---|---|---|---|---|---|
5 μM | 10 μM | 50 μM | 5 μM | 10 μM | 50 μM | |
LoVo Dx | 0.7 ± 0.01 | 0.5 ± 0.01 | 0.5 ± 0.02 | 0.5 ± 0.0 | 0.02 ± 0.01 | 0.2 ± 0.0 |
WiDr | 1.0 ± 0.01 | 4.0 ± 0.1 | 1.0 ± 0.05 | 2.0 ± 0.03 | 5.0 ± 0.02 | 5.0 ± 0.03 |
LRWZ | 3.0 ± 0.03 | 5.0 ± 0.02 | 4.0 ± 0.1 | 4.0 ± 0.01 | 21.0 ± 0.3 | 60.0 ± 1.3 |
LoVo | 2.0 ± 0.05 | 90.0 ± 2.3 | n.e.* | 3.0 ± 0.02 | n.e. | n.e. |