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Table 1 Clinical and molecular data on breast cancer patients (training set).

From: Predictors of primary breast cancers responsiveness to preoperative Epirubicin/Cyclophosphamide-based chemotherapy: translation of microarray data into clinically useful predictive signatures

Case Response Tumor reduction,% Histology pre Age ER PR BCL2 P53 KI67,% CerbB2 Grading
BC1492 NC 0 invasive lobular 50 0 0 0 1 28 0 2
BC1426 NC 0 invasive ductal + intraductal(40%) 62 1 1 400 0 2 1+ to 2+ 1 a. 2
BC1257 NC 0 invasive lobular 69 1 1 180 0 16 1+ to 2+ 2
BC1176 NC 0 invasive lobular a. tubular-lobular 47 1 1 130 0 7 0 2
BC1092 NC 0 invasive lobular a. ductal 66 1 1 0 0 10 0 2
BC1050 NC 0 invasive tubular-lobular; multifocal 60 1 1 60 0 3 0 2
BC1034 NC 0 intraductal a. invasive 43 1 1 0 0 2 0 2
BC1044 NC 0 invasive tubular-lobular 68 1 1 70 0 6 0 1
BC1466 pCR 100 invasive ductal a. intraductal(30%) 57 0 0 0 0 26 3+ 2
BC1255 pCR 100 invasive lobular 57 1 0 60 1 26 0 2
BC1254 pCR 100 medullary 62 0 0 0 0 70 1+ 3
BC1180 pCR 100 invasive lobular a. ductal 32 0 0 0 0 20 1+ 2
BC1159 pCR 100 invasive lobular a. ductal 40 0 0 70 0 70 1+ to 2+ 2
BC1042 pCR 100 non-typical medullary a. intraductal (bifocal) 38 0 0 10 0 35 0 3
BC1032 pCR 100 invasive lobular a. ductal 58 0 0 0 0 15 3+ 2
BC1443 PR/CR 94 invasive lobular a. ductal 61 1 0 10 0 30 3+ 2
BC1167 PR 0 invasive lobular 71 1 1 400 0 8 0 2
BC1162 PR 0 invasive lobular 66 1 1 70 0 7 1+ 2
BC1143 PR 0 invasive ductal a. intraductal(5%) 54 1 1 210 0 17 1+ 2
BC1138 PR 0 invasive lobular; multifocal 57 1 1 80 0 13 1+ 2
BC1100 PR 0 invasive tubular-lobular 55 1 1 140 0 4 0 1
BC1040 PR 0 invasive ductal 40 1 1 294 0 28 0 2
BC1170 PR 0 invasive lobular a. ductal bifocal 67 1 0 210 0 4 2+ to 3+ 2
BC1140 PR 10 left: invasive lobular 73 1 1 180 0 14 0 2
BC1418 PR 12 left:bifocal invasive tubular-lobular 57 1 0 300 0 7 2+ 1
BC1420 PR 15 invasive ductal a. lobular; multifocal 63 1 1 400 0 3 2+ 2
BC1491 PR 18 invasive lobular 64 1 1 300 0 7 0 2
BC1515 PR 20 invasive ductal 64 1 1 300 1 10 0 2
BC1445 PR 20 right:invasive lobular; bifocal 64 1 0 160 0 15 1+ to 2+ 2
BC1036 PR 24 invasive ductal 58 1 1 392 0 15 0 2
BC1308 PR 25 invasive lobular; multifocal 74 0 0 0 0 16 2+ 2
BC1133 PR 25 invasive ductal 53 0 0 294 0 50 0 3
BC1259 PR 32 invasive ductal a. lobular (Herd1) a. invasive ductal (Herd2) 59 1 0 300 0 16 2+ to 3+ 2
BC1498 PR 33 invasive ductal; bifocal 62 1 0 15 0 19 3+ 3
BJ_40613 PR 35 invasive ductal 61 1 1 100 0 4 2+ 2
BC1166 PR 35 invasive ductal a. lobular 45 1 1 140 0 14 1+ to 2+ 2
BC1142 PR 35 invasive lobular; bifocal 53 1 1 20 0 18 1+ 2
BC1422 PR 40 invasive ductal a. lobular; multifocal 53 1 1 360 0 2 2+ 2
BC1132 PR 40 invasive ductal 41 1 1 30 1 18 2+ 3
BC1096 PR 40 invasive ductal 46 1 1 294 0 13 0 2
BC1129 PR 42 invasive tubular-lobular 52 0 0 0 0 15 2+ 2
BC1130 PR 45 invasive lobular 42 1 1 140 0 NA 0 2
BC1131 PR 45 invasive ductal (pulmonal, ossar) 63 1 0 300 0 45 0 2
BC1256 PR 50 invasive lobular 60 0 0 0 1 17 1+ 2
BC1446 PR 50 invasive lobular; bifocal 53 1 1 140 0 35 1+ 2
BC1116 PR 53 invasive lobular 49 1 1 180 0 3 0 2
BC1415 PR 55 invasive lobular; multifocal 53 0 0 15 1 40 0 2
BC1141 PR 55 invasive lobular 52 1 1 500 0 20 0 2
BC1495 PR 60 invasive tubular a. intraductal (10%); bifocal 58 1 0 300 0 2 0 2
BC1497 PR 75 invasive lobular 42 1 1 300 0 5 2+ 2
BC1160 PR 75 invasive lobular 47 0 1 30 0 35 0 2
BC1038 PR 75 invasive ductal 35 1 1 294 0 30 0 2
BC1095 PR 85 invasive tubular-lobular 60 1 0 294 0 1 0 1
BC1024 PR 88 invasive lobular 59 1 1 70 0 18 0 2
BC1101 PR 75–85 invasive lobular; multifocal 75 1 0 180 0 10 3+ 2
BC1139 PR 89–90 invasive lobular with DCIS parts; multifocal 55 1 1 NA 0 15 NA 1
  1. ER and PgR status were determined by immunohistochemistry. 1 – positive (>7 fmol/mg protein); 0 – negative (<7 fmol/mg protein). HER2/neu status: copies of HER2/neu gene. Status of p53 oncogene: 0 - <180 score; 1 - >180 score. NA – not available.