Table 1 Clinical and molecular data on breast cancer patients (training set).
Case | Response | Tumor reduction,% | Histology pre | Age | ER | PR | BCL2 | P53 | KI67,% | CerbB2 | Grading |
|---|---|---|---|---|---|---|---|---|---|---|---|
BC1492 | NC | 0 | invasive lobular | 50 | 0 | 0 | 0 | 1 | 28 | 0 | 2 |
BC1426 | NC | 0 | invasive ductal + intraductal(40%) | 62 | 1 | 1 | 400 | 0 | 2 | 1+ to 2+ | 1 a. 2 |
BC1257 | NC | 0 | invasive lobular | 69 | 1 | 1 | 180 | 0 | 16 | 1+ to 2+ | 2 |
BC1176 | NC | 0 | invasive lobular a. tubular-lobular | 47 | 1 | 1 | 130 | 0 | 7 | 0 | 2 |
BC1092 | NC | 0 | invasive lobular a. ductal | 66 | 1 | 1 | 0 | 0 | 10 | 0 | 2 |
BC1050 | NC | 0 | invasive tubular-lobular; multifocal | 60 | 1 | 1 | 60 | 0 | 3 | 0 | 2 |
BC1034 | NC | 0 | intraductal a. invasive | 43 | 1 | 1 | 0 | 0 | 2 | 0 | 2 |
BC1044 | NC | 0 | invasive tubular-lobular | 68 | 1 | 1 | 70 | 0 | 6 | 0 | 1 |
BC1466 | pCR | 100 | invasive ductal a. intraductal(30%) | 57 | 0 | 0 | 0 | 0 | 26 | 3+ | 2 |
BC1255 | pCR | 100 | invasive lobular | 57 | 1 | 0 | 60 | 1 | 26 | 0 | 2 |
BC1254 | pCR | 100 | medullary | 62 | 0 | 0 | 0 | 0 | 70 | 1+ | 3 |
BC1180 | pCR | 100 | invasive lobular a. ductal | 32 | 0 | 0 | 0 | 0 | 20 | 1+ | 2 |
BC1159 | pCR | 100 | invasive lobular a. ductal | 40 | 0 | 0 | 70 | 0 | 70 | 1+ to 2+ | 2 |
BC1042 | pCR | 100 | non-typical medullary a. intraductal (bifocal) | 38 | 0 | 0 | 10 | 0 | 35 | 0 | 3 |
BC1032 | pCR | 100 | invasive lobular a. ductal | 58 | 0 | 0 | 0 | 0 | 15 | 3+ | 2 |
BC1443 | PR/CR | 94 | invasive lobular a. ductal | 61 | 1 | 0 | 10 | 0 | 30 | 3+ | 2 |
BC1167 | PR | 0 | invasive lobular | 71 | 1 | 1 | 400 | 0 | 8 | 0 | 2 |
BC1162 | PR | 0 | invasive lobular | 66 | 1 | 1 | 70 | 0 | 7 | 1+ | 2 |
BC1143 | PR | 0 | invasive ductal a. intraductal(5%) | 54 | 1 | 1 | 210 | 0 | 17 | 1+ | 2 |
BC1138 | PR | 0 | invasive lobular; multifocal | 57 | 1 | 1 | 80 | 0 | 13 | 1+ | 2 |
BC1100 | PR | 0 | invasive tubular-lobular | 55 | 1 | 1 | 140 | 0 | 4 | 0 | 1 |
BC1040 | PR | 0 | invasive ductal | 40 | 1 | 1 | 294 | 0 | 28 | 0 | 2 |
BC1170 | PR | 0 | invasive lobular a. ductal bifocal | 67 | 1 | 0 | 210 | 0 | 4 | 2+ to 3+ | 2 |
BC1140 | PR | 10 | left: invasive lobular | 73 | 1 | 1 | 180 | 0 | 14 | 0 | 2 |
BC1418 | PR | 12 | left:bifocal invasive tubular-lobular | 57 | 1 | 0 | 300 | 0 | 7 | 2+ | 1 |
BC1420 | PR | 15 | invasive ductal a. lobular; multifocal | 63 | 1 | 1 | 400 | 0 | 3 | 2+ | 2 |
BC1491 | PR | 18 | invasive lobular | 64 | 1 | 1 | 300 | 0 | 7 | 0 | 2 |
BC1515 | PR | 20 | invasive ductal | 64 | 1 | 1 | 300 | 1 | 10 | 0 | 2 |
BC1445 | PR | 20 | right:invasive lobular; bifocal | 64 | 1 | 0 | 160 | 0 | 15 | 1+ to 2+ | 2 |
BC1036 | PR | 24 | invasive ductal | 58 | 1 | 1 | 392 | 0 | 15 | 0 | 2 |
BC1308 | PR | 25 | invasive lobular; multifocal | 74 | 0 | 0 | 0 | 0 | 16 | 2+ | 2 |
BC1133 | PR | 25 | invasive ductal | 53 | 0 | 0 | 294 | 0 | 50 | 0 | 3 |
BC1259 | PR | 32 | invasive ductal a. lobular (Herd1) a. invasive ductal (Herd2) | 59 | 1 | 0 | 300 | 0 | 16 | 2+ to 3+ | 2 |
BC1498 | PR | 33 | invasive ductal; bifocal | 62 | 1 | 0 | 15 | 0 | 19 | 3+ | 3 |
BJ_40613 | PR | 35 | invasive ductal | 61 | 1 | 1 | 100 | 0 | 4 | 2+ | 2 |
BC1166 | PR | 35 | invasive ductal a. lobular | 45 | 1 | 1 | 140 | 0 | 14 | 1+ to 2+ | 2 |
BC1142 | PR | 35 | invasive lobular; bifocal | 53 | 1 | 1 | 20 | 0 | 18 | 1+ | 2 |
BC1422 | PR | 40 | invasive ductal a. lobular; multifocal | 53 | 1 | 1 | 360 | 0 | 2 | 2+ | 2 |
BC1132 | PR | 40 | invasive ductal | 41 | 1 | 1 | 30 | 1 | 18 | 2+ | 3 |
BC1096 | PR | 40 | invasive ductal | 46 | 1 | 1 | 294 | 0 | 13 | 0 | 2 |
BC1129 | PR | 42 | invasive tubular-lobular | 52 | 0 | 0 | 0 | 0 | 15 | 2+ | 2 |
BC1130 | PR | 45 | invasive lobular | 42 | 1 | 1 | 140 | 0 | NA | 0 | 2 |
BC1131 | PR | 45 | invasive ductal (pulmonal, ossar) | 63 | 1 | 0 | 300 | 0 | 45 | 0 | 2 |
BC1256 | PR | 50 | invasive lobular | 60 | 0 | 0 | 0 | 1 | 17 | 1+ | 2 |
BC1446 | PR | 50 | invasive lobular; bifocal | 53 | 1 | 1 | 140 | 0 | 35 | 1+ | 2 |
BC1116 | PR | 53 | invasive lobular | 49 | 1 | 1 | 180 | 0 | 3 | 0 | 2 |
BC1415 | PR | 55 | invasive lobular; multifocal | 53 | 0 | 0 | 15 | 1 | 40 | 0 | 2 |
BC1141 | PR | 55 | invasive lobular | 52 | 1 | 1 | 500 | 0 | 20 | 0 | 2 |
BC1495 | PR | 60 | invasive tubular a. intraductal (10%); bifocal | 58 | 1 | 0 | 300 | 0 | 2 | 0 | 2 |
BC1497 | PR | 75 | invasive lobular | 42 | 1 | 1 | 300 | 0 | 5 | 2+ | 2 |
BC1160 | PR | 75 | invasive lobular | 47 | 0 | 1 | 30 | 0 | 35 | 0 | 2 |
BC1038 | PR | 75 | invasive ductal | 35 | 1 | 1 | 294 | 0 | 30 | 0 | 2 |
BC1095 | PR | 85 | invasive tubular-lobular | 60 | 1 | 0 | 294 | 0 | 1 | 0 | 1 |
BC1024 | PR | 88 | invasive lobular | 59 | 1 | 1 | 70 | 0 | 18 | 0 | 2 |
BC1101 | PR | 75–85 | invasive lobular; multifocal | 75 | 1 | 0 | 180 | 0 | 10 | 3+ | 2 |
BC1139 | PR | 89–90 | invasive lobular with DCIS parts; multifocal | 55 | 1 | 1 | NA | 0 | 15 | NA | 1 |