Table 1 Patient characteristics
From: T cell responses against tumor associated antigens and prognosis in colorectal cancer patients
Peripheral spontaneous T cell response against TAA | Positive | Negative (matched) | Negative (total) | |
|---|---|---|---|---|
Number of patients | 16 | 16 | 38 | |
Age at first diagnosis, mean ± SD | 61.2 ± 12.1 | 59.9 ± 9.1 | 60.8 ± 11.1 | |
Male/Female | 11/5 | 11/5 | 19/19 | |
Duration of disease until T cell analysis (mean) | 31.8 | 30.2 | 27.4 | |
Stage (UICC) | I | 0 | 0 | 1 (2.6%) |
| Â | II | 2 (12.5%) | 2 (12.5%) | 18 (47.4%) |
| Â | III | 3 (18.8%) | 3 (18.8%) | 5 (13.2%) |
| Â | IV | 11 (68.8%) | 11 (68.8%) | 14 (36.8%) |
Previous therapy | CT | 9 (56.3%) | 12 (75%) | 18 (47.4%) |
| Â | RT | 3 (18.8%) | 4 (25%) | 7 (18.4%) |
| Â | Surgery | 12 (75%) | 14 (87.5%) | 30 (78.9%) |
Patients without evidence of tumor at time of blood draw | 4 (25%, 2 II, 2 III) | 4 (25%, 2 II, 2 III) | 17 (45%, 13 II, 3 III, 1 IV) | |
Time from blood draw until death or last contact, mean ± SD | 28.1 ± 19.2 | 27.4 ± 15.0 | 25.7 ± 14.0 | |