Figure 2

46 proteins identified by MALDI-TOF-MS from multiple gels derived both from melanoma and neuronal cells. X-axis = Protein names (abbreviations): Y-axis = frequency or # of times a protein is detected and confirmed by mass spectrometry from multiple gels. Pink bars represent proteins in neuronal cells and Blue bars indicate proteins present in melanoma cells. Protein names, abbreviations and accession numbers are from SWISS-PROT database used for protein identification (See Table 1-3 for details). One asterisk (*) indicates that the protein is detected in single, non-complexed form only in neuronal cells and two asterisks (**) indicate that this protein is detected as single protein only in melanoma cells. A: From left to right, expression of 12 proteins detected exclusively in trans-differentiated neuronal cells; 3 proteins were detected in single (non-complexed) form only and are marked by (*) and 9 proteins were expressed as complexes with other proteins. B: Two proteins were detected in melanoma cells only (i.e. NOT detected in neuronal cells); CDNA was expressed as a single protein (**) and MMO7 was present in a complex form. C: Expression frequencies of 32 proteins expressed both in melanoma and neuronal cells. Left side of the graph displays proteins that are detected at higher frequency in melanoma and the right side shows proteins that are detected at a higher frequency in trans-differentiated neuronal cells.