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Table 2 Number and percentage of subjects with detectable CTL responses, by group

From: CD8+ T lymphocyte responses target functionally important regions of Protease and Integrase in HIV-1 infected subjects

Group

Protease

Integrase

Number of subjects with any response (%)

Mean responsea

Number of subjects with any response (%)

Mean responsea

Acute

Total

7/28 (25)

221

18/28 (64)

378

 

On therapyb

3/17 (18)

---

9/17 (53)

---

 

Off therapyb

4/13 (31)

---

10/13 (77)

---

Chronic

Total

4/22 (18)

204

15/22 (68)

281

 

On therapy

2/13 (15)

---

9/13 (69)

---

 

Off therapy

2/9 (22)

---

6/9 (67)

---

Controller

 

2/6 (33)

125

5/6 (83)

215

Overall

 

13/56 (23)

212

38/56 (68)

320

  1. a Values are SFC/million PBMC. b Two patients in the acute cohort were evaluated at two different time points, once on therapy, once off therapy.