Figure 8
From: Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells
BTC pretreatment induces resistance of human lung cancer cells to apoptosis induction by TNF-α/CHX. A549 cells (1 × 106/ml) were pretreated with BTC for 4 h, then stimulated with 20 ng/ml TNF-α/CHX for 24 h. The cells were stained with annexin V and PI and subjected to FACS assay of cellular apoptosis. ** stand for P- value less than 0.01 as compared to control (DMSO only), and ++ stand for P-value less than 0.01, as compared to BTC + DMSO. Data were presented as mean ± SEM of three independent experiments.