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Table 1 Overview of patients enrolled within the clinical trial

From: Results of a phase I/II clinical trial: standardized, non-xenogenic, cultivated limbal stem cell transplantation

Total LSCD
No. AGE SEX LSCD etiology Type Follow-up (months) VA before VA after Tx Post LEC TX Result
1 44 M Chemical burn allo* auto 41 CF (0.014) CF (0.014) PK Failed
2 45 F Chemical burn auto 43 HM (0.005) 0,05 - AS, FS
4 45 M Chemical burn auto 31 CF (0.014) <0,05 - Failed
5 6 M Chemical burn auto 31 HM (0.005) LP (0) PK Failed
6 27 M Aniridia allo** 27 0.053 0.1 PK AS, FS
7 70 F Corneal ulcer auto 25 LP (0) HM (0.005) PK AS, FS
8 29 M Chemical burn auto 25 <0,05 HM (0.005) - Failed
10 33 M Chemical burn auto 19 LP (0) LP (0) - Failed
11 63 M Iatrogenic auto 19 HM (0.005) HM (0.005) - AS
13 31 F Aniridia allo** 48 CF (0.014) 0.2 PK AS, FS
14 16 F Kniest syndrome auto 6 LP (0) HM (0.005) - AS
15 6 M Keratitis auto 5 LP (0) LP (0) - Failed
16 48 M Chemical burn auto 4 CF (0.014) 0.125 - AS, FS
17 79 M Trauma auto 4 CF (0.014) CF (0.014) - AS
18 42 F Viral keratitis auto 18 LP (0) HM (0.005) PK AS, FS
Partial LSCD
No. AGE SEX LSCD Etiology Type Follow-up (months) VA before VA after Tx Post LEC TX Result
3 57 F Iatrogenic auto 39 0.15 0,16 - AS, FS
9 44 F Keratitis, uveitis auto 24 CF (0.014) 0.15 PK AS, FS
12 47 M Trauma auto 18 0.2 0.9 - AS, FS
  1. The table shows the subject code, age, sex, etiology of LCSD (Limbal Stem Cell Deficency), type of donor (allo* = allogenic cadaveric, allo** = from living related donor), the follow-up, visual acuities pre and post op (LP = light perception, CF = counting fingers, HM = hand movements) surgical interventions following LEC TX (Limbal epithelial cell transplant) particularly PK (penetrating keratoplasty) procedures and the vision at most recent follow-up (AS = anatomical success, FS = functional success).