Figure 2From: Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis Effect of ascorbic acid infusion on Sequential Organ Failure Assessment (SOFA) score (days 0–4). Daily mean SOFA scores decreased over time with both doses of ascorbic acid infusion (p < 0.05 significantly non-zero) with the higher dose significantly less than placebo (Hi-AscA vs. placebo p < 0.01). Placebo (О), Lo-AscA (▼), Hi-AscA (▲).Back to article page