Table 4 Correlation between metabolic phenotypes of tumor and clinicopathologic factors
From: Metabolic phenotypes in primary unknown metastatic carcinoma
| Parameters | Glycolysis type | Glutaminolysis type | Mitochondrial type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes | No | p-value | Yes | No | p-value | Yes | No | p-value | |
| n = 33 (%) | n = 44 (%) | n = 43 (%) | n = 34 (%) | n = 74 (%) | n = 3 (%) | ||||
| Age | 0.087 | 0.340 | 1.000 | ||||||
| <50 | 7 (21.2) | 18 (40.9) | 16 (37.2) | 9 (26.5) | 24 (32.4) | 1 (33.3) | |||
| ≥50 | 26 (78.8) | 26 (59.1) | 27 (62.8) | 25 (73.5) | 50 (67.6) | 2 (66.7) | |||
| Sex | 0.342 | 1.000 | 1.000 | ||||||
| Male | 23 (69.7) | 25 (56.8) | 27 (62.8) | 21 (61.8) | 46 (62.2) | 2 (66.7) | |||
| Female | 10 (30.3) | 19 (43.2) | 16 (37.2) | 13 (38.2) | 28 (37.8) | 1 (33.3) | |||
| Clinical subtype | 0.371 | 0.971 | 0.687 | ||||||
| Nodal type | 18 (54.5) | 16 (36.4) | 18 (41.9) | 16 (47.1) | 33 (44.6) | 1 (33.3) | |||
| Single organ type | 5 (15.2) | 10 (22.7) | 9 (20.9) | 6 (17.6) | 15 (20.3) | 0 (0.0) | |||
| Intermediate type | 6 (18.2) | 8 (18.2) | 8 (18.6) | 6 (17.6) | 13 (17.6) | 1 (33.3) | |||
| Carcinomatosis type | 4 (12.1) | 10 (22.7) | 8 (18.6) | 6 (17.6) | 13 (17.6) | 1 (33.3) | |||
| Histologic type | 0.093 | 0.545 | 0.208 | ||||||
| AD | 11 (33.3) | 16 (36.4) | 17 (39.5) | 10 (29.4) | 26 (35.1) | 1 (33.3) | |||
| PD | 4 (12.1) | 12 (27.3) | 8 (18.6) | 8 (23.5) | 14 (18.9) | 2 (66.7) | |||
| SQ | 13 (39.4) | 7 (15.9) | 9 (20.9) | 11 (32.4) | 20 (27.0) | 0 (0.0) | |||
| UP | 5 (15.2) | 9 (20.5) | 9 (20.9) | 5 (14.7) | 14 (18.9) | 0 (0.0) | |||
| Organs involved | 0.392 | 0.730 | 0.026 | ||||||
| Lymph node | 24 (72.7) | 25 (56.8) | 27 (62.8) | 22 (64.7) | 48 (64.9) | 1 (33.3) | |||
| Bone | 3 (9.1) | 7 (15.9) | 7 (16.3) | 3 (8.8) | 10 (13.5) | 0 (0.0) | |||
| Brain | 4 (12.1) | 5 (11.4) | 4 (9.3) | 5 (14.7) | 9 (12.2) | 0 (0.0) | |||
| Other | 2 (6.1) | 7 (15.9) | 5 (11.6) | 4 (11.8) | 7 (9.5) | 2 (66.7) | |||