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Table 3 Datasets analyzed by RCR used as negative controls

From: A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability

Dataset name Dataset ID PubMed ID Species Experimental context Tissue/cell type Perturbation Time point Independent endpoint Control
Hs_NHBE_CDKinh_rel_vs_blk_8 h E-MTAB-1272 23926424 Hs in vitro NHBE Exposure to CDK4/6 inhibitor 24 exposure + 8 h after removal of inhibitor FACS, cell cycle analysis Untreated
Hs_MVEC-C_hpx_vs_ct_24 h GSE11341 18469115 Hs In vitro Primary cardiac microvascular ECs 24 h hypoxia (1% O2)    Normoxia (21% O2)
Hs_MVEC-L_hpx_vs_ct_24 h GSE11341 18469115 Hs In vitro Primary human pulmonary microvascular ECs 24 h hypoxia (1% O2)    Normoxia (21% O2)
Hs_JurkT_ars_vs_ct GSE46909 23824090 Hs In vitro Jurkat T cells Arsenic trioxide 3 μM 6 h exposure   Untreated
  1. Hs_NHBE_CDKinh_rel_vs_blk_8h, Hs_MVEC-C_hpx_vs_ct_24h, Hs_MVEC-L_hpx_vs_ct_24h and Hs_JurkT_ars_vs_ct were used as a negative control datasets. ECs: endothelial cells; HAECs: human aortic endothelial cells; HCAECs: human coronary artery ECs; GFP: green fluorescent protein; OxPAPC: oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; oxLDL: oxidized low density lipoprotein; IHS: immunohistochemistry; FACS: fluorescence-activated cell sorting; eQTL: expression quantitative trait loci; Hs: homo sapiens; IMA: internal mammary artery; Mm: mus musculus, MVECs: microvascular ECs; NHBE: normal human bronchial epithelial cells; h: hours; d: days; wk: weeks; yr: years.