Table 3 Genes down regulated in HL-60 cells treated with PLVX-MT-3 compared with control group

1

CUL3

cullin 3

10.4408

0.6273

0.0601

0.008493

2

MAPK8IP2

mitogen-activated protein kinase 8 interacting protein 2

3.6692

0.5249

0.1431

0.009149

3

NTF3

neurotrophin 3

2.5110

0.4725

0.1882

0.009344

4

CCL2

chemokine (C-C motif) ligand 2

88.1973

18.1459

0.2057

0.009402

5

HSPA1B

heat shock 70 kDa protein 1B

9152.4687

2147.2853

0.2346

0.00949

6

PRKCA

protein kinase C, alpha

259.7601

68.8275

0.2650

0.009593

7

ALOX15B

arachidonate 15-lipoxygenase, type B

2.2320

0.6779

0.3037

0.009776

8

SST

somatostatin

5.9015

1.9173

0.3249

0.009921

9

SEMA4D

sema domain, immunoglobulin domain 4D

82.5241

27.6746

0.3354

0.010009

10

CARD18

caspase recruitment domain family, member 18

6.4031

2.1791

0.3403

0.010055

11

NAIP

NLR family, apoptosis inhibitory protein

374.1656

136.0874

0.3637

0.010316

12

FADD

Fas (TNFRSF6)-associated via death domain

2746.1986

1001.6552

0.3647

0.010329

13

FAIM2

Fas apoptotic inhibitory molecule 2

34.8320

13.2906

0.3816

0.010573

14

CARD9

caspase recruitment domain family, member 9

44.1602

16.8715

0.3821

0.01058

15

ALOX12

arachidonate 12-lipoxygenase

82.6640

32.4829

0.3930

0.010768

16

CARD8

caspase recruitment domain family, member 8

32.5951

12.9265

0.3966

0.010835

17

CASP10

caspase 10, apoptosis-related cysteine peptidase

114.4506

45.4485

0.3971

0.010845