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Table 4 Detailed evaluation of discordant results between methods

From: The validation of a novel method combining both HER2 immunohistochemistry and HER2 dual-colour silver in situ hybridization on one slide for gastric carcinoma testing

 

Single methods

Combined method

Case

Histology (Lauren)

IHC (Score)

SISH (≥ 2.0/< 2.0)

IHC (Score)

SISH (≥ 2.0/< 2.0)

6693

i

2+

≥2.0

3+

≥2.0

9924

i

2+

<2.0

1+

<2.0

20209

i

2+

≥2.0

3+

≥2.0

1057

d

3+

<2.0

2+

<2.0

  1. Abbreviations: IHC immunohistochemistry, SISH silver in situ hybridization.