Figure 6
p21 WAF1/CIP1 labeling index in HBV-related multistep hepatocarcinogenesis and the correlations thereof with stathmin and elongation factor 1α (EF1α) expression. A. Box plots show p21WAF1/CIP1 labeling index in normal liver (NL), liver cirrhosis (LC), low-grade dysplastic nodules (LGDN), high-grade dysplastic nodules (HGDN), and hepatocellular carcinoma (HCC). ‡ Statistical significance (linear trend model, P < 0.05). B. Correlations between p21WAF1/CIP1 labeling index and TIF. C-D. Correlations between p21WAF1/CIP1 labeling index and stathmin mRNA (C) and stathmin protein levels (D). E. Correlations between p21WAF1/CIP1 labeling index and EF1α protein levels. *Statistical significance (P < 0.05).