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Table 1 Association between GOLPH3 expression and clinicopathological variables of CRC patients treated with 5-FU-based adjuvant chemotherapy

From: GOLPH3 predicts survival of colorectal cancer patients treated with 5-fluorouracil-based adjuvant chemotherapy

Variables Cases GOLPH3 expression P
   Low High  
Age     
   <60 yr 58 32 26 0.718
   ≥60 yr 72 42 30  
Gender     
   Female 50 21 29 0.007
   Male 80 53 27  
Tumor location     
   Colon 104 62 42 0.215
Rectum 26 12 14  
Tumor size     
   ≤4 cm 43 24 19 0.858
   >4 cm 87 50 37  
Depth of Invasion     
   T1/T2 13 7 6 0.813
   T3/T4 117 67 50  
Lymph node metastasis     
   Negative 50 24 26 0.104
   Positive 80 50 30  
Distant metastasis     
   Negative 105 56 49 0.090
   Positive 25 18 7  
TNM stage     
   II 45 21 24 0.086
   III/IV 85 53 32  
Histological type     
   Adenocarcinoma 121 70 51 0.498
   Mucinous 9 4 5  
Tumor differentiation     
   Well 17 10 7 0.812
   Moderate 87 49 38  
   Poor 17 11 6  
   Unknown 9    
Recurrence     
   Negative 83 42 41 0.006
   Positive 42 32 10  
   Unknown 5    
Survival     
   Alive 82 40 42 0.014
   Dead 48 34 14  
  1. P values in bold were statistically significant.