GOLPH3 predicts survival of colorectal cancer patients treated with 5-fluorouracil-based adjuvant chemotherapy

Table 1 Association between GOLPH3 expression and clinicopathological variables of CRC patients treated with 5-FU-based adjuvant chemotherapy

Variables	Cases	GOLPH3 expression		P
		Low	High
Age
<60 yr	58	32	26	0.718
≥60 yr	72	42	30
Gender
Female	50	21	29	0.007
Male	80	53	27
Tumor location
Colon	104	62	42	0.215
Rectum	26	12	14
Tumor size
≤4 cm	43	24	19	0.858
>4 cm	87	50	37
Depth of Invasion
T1/T2	13	7	6	0.813
T3/T4	117	67	50
Lymph node metastasis
Negative	50	24	26	0.104
Positive	80	50	30
Distant metastasis
Negative	105	56	49	0.090
Positive	25	18	7
TNM stage
II	45	21	24	0.086
III/IV	85	53	32
Histological type
Adenocarcinoma	121	70	51	0.498
Mucinous	9	4	5
Tumor differentiation
Well	17	10	7	0.812
Moderate	87	49	38
Poor	17	11	6
Unknown	9
Recurrence
Negative	83	42	41	0.006
Positive	42	32	10
Unknown	5
Survival
Alive	82	40	42	0.014
Dead	48	34	14

ISSN: 1479-5876