Figure 2

Effect of bevacizumab (Bev) on glioma cell migration and invasion in vitro . (A) The migratory ability of C6 glioma cells treated with 5 mg/ml Bev was evaluated by wound healing assay. The representative images at 0 hour and 24 hours post-wounding are shown at 100 × magnification. (B) C6 glioma cell invasion was evaluated by transwell assay after 5 mg/ml Bev treatment for 24 hours. The stained invasive cells were photographed under an inverted light microscope at 100 × magnification. (C) Quantitative results of C6 glioma cell invasion in vitro. The experiments were performed in triplicate with three independent experiments.