Table 2 Tumour response in all patients
Patients, n(%) | |||||||
|---|---|---|---|---|---|---|---|
Response according to irRC | Total (N = 833) | BRAF-mutation positive (n = 169) | BRAF wildtype (n = 291) | NRAS-mutation positive (n = 14) | NRAS wildtype (n = 67) | Any irAE (n = 278) | No irAE (n = 555) |
irCR | 29 (3) | 9 (6) | 12 (4) | 2 (14) | 4 (6) | 10 (4) | 19 (3) |
irPR | 82 (10) | 19 (11) | 27 (9) | 2 (14) | 9 (13) | 31 (11) | 51 (9) |
irSD | 175 (21) | 36 (21) | 76 (26) | 4 (29) | 20 (30) | 57 (21) | 118 (21) |
irPD | 547 (66) | 105 (62) | 176 (61) | 6 (43) | 34 (51) | 180 (65) | 367 (66) |
irDCR | 286 (34) | 64 (38) | 115 (39) | 8 (57) | 33 (49) | 98 (35) | 188 (34) |