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Table 4 Relationships between serum sCD40L and pro-angiogenic or immunosuppressive cytokines in patients with PDAC in the validation dataset

From: Clinical significance of elevated serum soluble CD40 ligand levels as a diagnostic and prognostic tumor marker for pancreatic ductal adenocarcinoma

(All groups)   EGF VEGF IL-8 IL-6 IL-10 IL-1RA
Serum sCD40L p ) 0.590 0.389 0.195 0.203 0.215 0.243
  (p- value) < 0.001 < 0.001 0.037 0.029 0.021 0.009
(PDAC group)   EGF VEGF IL-8 IL-6 IL-10 IL-1RA
Serum sCD40L p ) 0.397 0.305 0.257 0.209 0.224 0.248
  (p- value) 0.003 0.026 0.058 0.126 0.100 0.068
  1. Pro-angiogenic cytokines, EGF, VEGF, and IL-8; immunosuppressive cytokines, IL-6, IL-10, and IL-1RA.
  2. γp, Pearson’s correlation coefficient.
  3. p < 0.05 (two-tailed) was considered to be statistically significant.
  4. Statistically significant values are given in bold type.