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Table 1 Clinical, demographic and biochemical characteristics

From: Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios

Variable Study population (n=350)
Age [years, median (IQR)] 62 (59–66)
Females (%) 52.6
Current smoker (%) 7.7
Current alcohol use (%) 72.2
Body mass index [Kg/m2, median (IQR)] 28.0 (25.7-31.2)
Daily number of steps [median (IQR)] 6,903 (4,718-8,824)
Systolic blood pressure (mmHg, mean±SD) 135±16
Diastolic blood pressure (mmHg, mean±SD) 80±10
Heart rate (b/min, mean±SD) 66±10
Hypertension (%) 43.8
Rheumatoid arthritis (%) 5.2
Diabetes (%) 1.7
Hypercholesterolaemia (%) 36.7
Cardiovascular risk score [%, median (IQR)] 7 (4–10)
Low (%) 70.9
Moderate (%) 22.5
High (%) 6.6
Non steroidal anti-inflammatory drugs (%) 8.9
Beta-blockers (%) 17.0
Angiotensin converting enzyme inhibitors (%) 42.2
Calcium-channel blockers (%) 9.6
Statins (%) 28.1
Diuretics (%) 10.0
Antidiabetic drugs (%) 1.5
Folic acid supplements (%) 1.4
Fasting serum glucose [mmol/L, median (IQR)] 4.8 (4.4-5.2)
Total cholesterol (mmol/L, mean±SD) 5.2±0.9
LDL-cholesterol (mmol/L, mean±SD) 3.2±0.8
HDL-cholesterol [mmol/L, median (IQR)] 1.3 (1.1-1.5)
Triglycerides [mmol/L, median (IQR)] 1.1 (0.8-1.6)
eGFRa (mL/min, mean±SD) 81±16
C-reactive protein [mg/L, median (IQR)] 1.9 (1.2-3.5)
Homocysteine [μmol/L, median (IQR)] 8.8 (7.6-10.5)
Cysteine (μmol/L, mean±SD) 183.1±36.5
Taurine [μmol/L, median (IQR)] 62.0 (51.6-83.6)
Glutamylcysteine (μmol/L, mean±SD) 4.2±1.1
Glutathione [μmol/L, median (IQR)] 3.9 (3.0-5.2)
Cysteinylglycine [μmol/L, median (IQR)] 28.6 (25.2-32.9)
  1. a: calculated using the Modification of Diet in Renal Disease formula.