Figure 4

Gene expression patterns 10 weeks after ischemia reperfusion injury performed on all samples and comparing non-infarct area versus infarct area. (A) Determination of 92 representative genes followed by 2 dimensional hierarchical clustering and visualization as heatmap. Each sample forms a column and each gene forms a row with the heatmap intensities standardized within each gene. Overall 5 independent samples were measured for each group and two different tissue areas (infarct and non-infarct ventricular tissue) resulting in a final number of 40 samples. (B) Principle component analysis (PCA) of the same data reflecting the total expression changes into two uncorrelated principal components.