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Table 2 The list of predicted target genes of miRNA-15b after selection

From: Dynamically expressed microRNA-15b modulates the activities of CD8+ T lymphocytes in mice with Lewis lung carcinoma

Target gene

Gene name

Possible function

Sites

   

Conserved

Poorly conserved

CD28

CD28 molecule

activation

1(8mer)

0

TRAF3

TNF receptor-associated factor 3

apoptosis

1(7mer-m8)

3(8mer)

DEDD

death effector domain containing

apoptosis

1(7mer-m8)

2(7mer-m8, 7mer-1A)

IRAK2

interleukin-1 receptor-associated kinase 2

apoptosis

1(8mer)

0

E2F3

E2F transcription factor 3

proliferation

1(8mer)

1(7mer-m8)

PDCD6IP

programmed cell death 6 interacting protein

Cell cycle

1(7mer-m8)

1(7mer-m8)

LITAF

lipopolysaccharide-induced TNF factor

apoptosis

1(7mer-m8)

0

IL-15

Interleukin-15

activation

1(7mer-m8)

0