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Figure 1 | Journal of Translational Medicine

Figure 1

From: Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model

Figure 1

Comparison of hMUC1 expression in lung tissues and tumors from MUC1.Tg vs. wild type mice at week 38. (A) Lung tissue from a MUC1.Tg control mouse exhibiting hMUC1 positivity and normal H&E staining. (B) Lung tissue from a urethane-treated wild type mouse exhibiting hMUC1-negative adenoma; the H & E staining shows a representative tumor region (arrow). (C) Lung tissue from a urethane-treated MUC1.Tg mouse exhibiting hMUC1-positive adenoma; the H&E staining shows a representative tumor region (arrow). Magnification = 60X (all panels). A number of samples showed tumors with multiple foci.

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