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Table 2 Univariate and multivariate cox regression analysis for disease-free survival and overall survival in patients with laryngeal squamous cell carcinoma

From: Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma

 

Disease-free survival

Overall survival

 

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

Factors

RR(95% CI)

P valuea

RR(95% CI)

P valuea

RR(95% CI)

P valuea

RR(95% CI)

P valuea

Ageb

0.997(0.492 -2.019)

0.397

  

1.026(0.507 -2.078)

0.337

  

Sexc

0.997(0.492 -2.020)

0.560

  

1.026(0.507 -2.079)

0.457

  

Tumor locationd

0.997(0.492 -2.021)

0.053

  

1.026(0.507 -2.080)

0.085

  

Pathology gradee

0.997(0.492 -2.022)

0.003

1.074(0.643 -1.795)

0.786

1.026(0.507 -2.081)

0.003

1.055(0.632 -1.763)

0.837

pT stagef

0.997(0.492 -2.023)

0.013

1.074(0.643 -1.796)

0.434

1.026(0.507 -2.082)

0.013

1.055(0.632 -1.764)

0.291

Pathology TNM statusg

0.997(0.492 -2.024)

0.002

1.074(0.643 -1.797)

0.886

1.026(0.507 -2.083)

0.003

1.055(0.632 -1.765)

0.848

Treatmenth

0.997(0.492 -2.025)

0.005

1.074(0.643 -1.798)

0.167

1.026(0.507 -2.084)

0.015

1.055(0.632 -1.766)

0.164

pN stageI

0.997(0.492 -2.026)

<0.001

1.074(0.643 -1.799)

0.04

1.026(0.507 -2.085)

<0.001

1.055(0.632 -1.767)

0.03

PTK6k expression

0.997(0.492 -2.027)

0.002

1.074(0.643 -1.800)

0.029

1.026(0.507 -2.086)

0.002

1.055(0.632 -1.768)

0.038

  1. a Cox proportional hazards model;b ≤58 years versus > 58 years;c Male versus female;d glottic versus supraglottic versus subglottic;e well versus mediate versus poor differential grade; f pT1/pT2 versus pT3 /pT4; g pathological I/II versus III/IV; h surgery versus surgery+ radiotherapy versus surgery+chemotherapy; I pN0 versus pN+; k High versus medium versus low expression; RR=relative risk; CI=confidence interval; pT= pathologic tumor; pN=pathologic node.