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Table 2 Univariate and multivariate cox regression analysis for disease-free survival and overall survival in patients with laryngeal squamous cell carcinoma

From: Low expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma

  Disease-free survival Overall survival
  Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Factors RR(95% CI) P valuea RR(95% CI) P valuea RR(95% CI) P valuea RR(95% CI) P valuea
Ageb 0.997(0.492 -2.019) 0.397    1.026(0.507 -2.078) 0.337   
Sexc 0.997(0.492 -2.020) 0.560    1.026(0.507 -2.079) 0.457   
Tumor locationd 0.997(0.492 -2.021) 0.053    1.026(0.507 -2.080) 0.085   
Pathology gradee 0.997(0.492 -2.022) 0.003 1.074(0.643 -1.795) 0.786 1.026(0.507 -2.081) 0.003 1.055(0.632 -1.763) 0.837
pT stagef 0.997(0.492 -2.023) 0.013 1.074(0.643 -1.796) 0.434 1.026(0.507 -2.082) 0.013 1.055(0.632 -1.764) 0.291
Pathology TNM statusg 0.997(0.492 -2.024) 0.002 1.074(0.643 -1.797) 0.886 1.026(0.507 -2.083) 0.003 1.055(0.632 -1.765) 0.848
Treatmenth 0.997(0.492 -2.025) 0.005 1.074(0.643 -1.798) 0.167 1.026(0.507 -2.084) 0.015 1.055(0.632 -1.766) 0.164
pN stageI 0.997(0.492 -2.026) <0.001 1.074(0.643 -1.799) 0.04 1.026(0.507 -2.085) <0.001 1.055(0.632 -1.767) 0.03
PTK6k expression 0.997(0.492 -2.027) 0.002 1.074(0.643 -1.800) 0.029 1.026(0.507 -2.086) 0.002 1.055(0.632 -1.768) 0.038
  1. a Cox proportional hazards model;b ≤58 years versus > 58 years;c Male versus female;d glottic versus supraglottic versus subglottic;e well versus mediate versus poor differential grade; f pT1/pT2 versus pT3 /pT4; g pathological I/II versus III/IV; h surgery versus surgery+ radiotherapy versus surgery+chemotherapy; I pN0 versus pN+; k High versus medium versus low expression; RR=relative risk; CI=confidence interval; pT= pathologic tumor; pN=pathologic node.