Table 1 List of target genes of miR-200c, miR-205, and miR-375 identified in breast cancer cell lines
miR | Target Gene | Accession No. | Name |
|---|---|---|---|
miR-200c | ANKH | NM_054027 | ankylosis, progressive homolog (mouse) |
| Â | AP1S2 | NM_003916 | adaptor-related protein complex 1, sigma 2 subunit |
| Â | CDH11 | NM_001797 | cadherin 11 |
| Â | CFL2 | NM_021914 | cofilin 2 (muscle) |
| Â | CRTAP | NM_006371 | cartilage associated protein |
| Â | DPY19L1 | NM_015283 | dpy-19-like 1 (C. elegans) |
| Â | DENND5B | NM_144973 | DENN/MADD domain containing 5B |
| Â | EMP1 | NM_001423 | epithelial membrane protein 1 |
| Â | FAM46C | NM_017709 | family with sequence similarity 46, member C |
| Â | FN1 | NM_212474 | fibronectin 1 |
| Â | FOXF2 | NM_001452 | forkhead box F2 |
| Â | FSCN1 | NM_003088 | fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) |
| Â | KANK2 | NM_001136191 | KN motif and ankyrin repeat domains 2 |
| Â | LAMC1 | NM_002293 | laminin, gamma 1 (formerly LAMB2) |
| Â | LHFP | NM_005780 | lipoma HMGIC fusion partner |
| Â | LOX | NM_001178102 | lysyl oxidase |
| Â | MCFD2 | NM_139279 | multiple coagulation factor deficiency 2 |
| Â | PAG1 | NM_018440 | phosphoprotein associated with glycosphingolipid microdomains 1microdomains 1 |
| Â | PDE7B | NM_018945 | phosphodiesterase 7B |
| Â | PPP1R18 | NM_133471 | protein phosphatase 1, regulatory subunit 18 |
| Â | PRKCA | NM_002737 | protein kinase C, alpha |
| Â | RGL1 | NM_015149 | ral guanine nucleotide dissociation stimulator-like 1 |
| Â | SEC23A | NM_006364 | Sec23 homolog A (S. cerevisiae) |
| Â | SPRED1 | NM_006931 | sprouty-related, EVH1 domain containing 1 |
| Â | TIMP2 | NM_003255 | TIMP metallopeptidase inhibitor 2 |
| Â | ZEB1 | NM_030751 | zinc finger E-box binding homeobox 1 |
| Â | ZEB2 | NM_014795 | zinc finger E-box binding homeobox 2 |
miR-205 | CALU | NM_001219 | calumenin |
| Â | PTPRJ | NM_002843 | protein tyrosine phosphatase, receptor type, J |
| Â | PTPRM | NM_001105244 | protein tyrosine phosphatase, receptor type, M |
miR-375 | DIP2C | NM_014974 | DIP2 disco-interacting protein 2 homolog C |
| Â | KIAA1199 | NM_018689 | KIAA1199, colon cancer secreted protein 1 |
| Â | LDHB | NM_002300 | lactate dehydrogenase B |
| Â | QKI | NM_006775 | quaking homolog, KH domain RNA binding |
| Â | SEC23A | NM_006364 | Sec23 homolog A (S. cerevisiae) |
| Â | SLC7A11 | NM_014331 | solute carrier family 7 |