Improvement of left ventricular remodeling after myocardial infarction with eight weeks L-thyroxine treatment in rats

Table 2 Changes in body weight, heart weight, and infarct size (whole heart tissue preps)

	N	Body Wt1 (gm)	Body Wt2 (gm)	Heart Wt (mg)	Hw/BWt2 (mg/gm)	LV Wt (mg)	RV Wt (mg)	Infarct length (mm)
Sham	9	253 (10)	268 (15)	762 (50)	2.8 (0.1)	563 (40)	138 (15)
MI	10	249 (23)	268 (19)	906 (90)**	3.4 (0.6)*	594 (63)	205 (75)	10.5 (0.7)
MI+T4	9	243 (15)	285 (22)	1217 (135)** ‡	4.3 (0.3)** ‡	793 (185)*	304 (68)**†	11.0 (0.7)
% (MI+T4 vs. MI)		−2	6	34	26	34	48	5

Data presented as means (SD).
N, total number of rats for whole heart tissue collection; Body Wt1, body weight before surgery; Body wt2, body weight at terminal study; Heart Wt, heart weight; Hw/BWt2, heart wt-to-body wt2 ratio; LV Wt, left ventricular weight; RV Wt, right ventricular weight; *, p < 0.05, **, p < 0.01 vs. Sham rats; †, p <0.05, ‡, p < 0.01 vs. MI rats; ANOVA with Student-Newman-Keuls’ or Dunnett T3’s (Heart Wt, Hw/BWt2, LV Wt and RV Wt) Multiple Comparison Test.

ISSN: 1479-5876