Figure 1

Effect of Th ₁ cytokines on pancreatic cancer cells. A) Shows reduced percentage of monocytic CD33⁺/CD11b⁺/CD14⁺/HLA-DR^- and granulocytic CD33⁺/CD11b⁺/CD15⁺/HLA-DR^- MDSC populations in the presence of aATC for MiaE (p<0.0021) and MiaM (p<0.046) in the presence of aATC or aATC+Th₁ cytokines [MiaE (p<0.00041) and MiaM (p <0.0002)] compared to control co-cultures (n=3). B) Shows that increased cytotoxicity by EGFRBi armed ATC after 3 days at an E:T ratio of 1:1 when grown in the presence of Th₁ cytokines.