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Table 2 Comparison of hypermethylation detection on HNSCC tumor specimens and normal control salivary rinse samples

From: TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors

Genes Control HNSCC Specificity% (95% CI) Senstivity% (95% CI)
Cases (n) M n (%) Cases (n) M n (%)
CCNA1 60 2 (3) 67 22 (33) 97 (93–101) 33 (21–45)
DAPK 39 1 (3) 68 35 (51) 97 (93–101) 51 (38–64)
MGMT 57 2 (4) 67 14 (21) 96 (91–101) 21 (11–31)
SFRP1 20 0 (0) 58 36 (62) 100 62 (50–74)
TIMP3 60 2 (3) 70 37 (53) 97 (93–101) 53 (40–66)
  1. M – Methylated.