Table 3 Urinary parameters at baseline, before (control), during (intervention) and after administration (follow-up) of the study preparation (n = 20; mean ± standard deviation)

Volume (mL/24 h)

2,379 ± 1,063

2,396 ± 858

2,322 ± 997

2,534 ±1,311

2,433 ± 1,194

0.888

0.550

0.526

0.765

pH

6.38 ± 0.37

6.36 ± 0.31

6.39 ± 0.38

6.39 ± 0.41

6.39 ± 0.21

0.365

0.823

0.667

0.926

Sodium (mmol/24 h)

157 ± 74

182 ± 51

155 ± 65

173 ± 58

179 ± 74

0.100

0.107

0.398

0.204

Potassium (mmol/24 h)

65 ± 29

71 ± 19

82 ± 24

77 ± 28

74 ± 23

0.287

0.044

0.190

0.232

Calcium (mmol/24 h)

4.02 ± 1.83

4.11 ± 1.70

3.85 ± 1.54

4.09 ± 1.51

4.47 ± 2.16

0.881

0.411

0.808

0.334

Magnesium (mmol/24 h)

5.14 ± 2.06

5.18 ± 1.95

4.68 ± 1.75

4.99 ± 1.87

5.56 ± 2.73

0.970

0.262

0.881

0.351

Ammonium (mmol/24 h)

28.1 ± 9.1

26.6 ± 7.2

28.0 ± 8.3

29.8 ± 9.4

30.0 ± 11.8

0.351

0.526

0.218

0.940

Chloride (mmol/24 h)

147 ± 71

178 ± 48

161 ± 68

158 ± 53

182 ± 82

0.026

0.391

0.070

0.052

Phosphate (mmol/24 h)

26.9 ± 8.6

28.2 ± 7.5

28.8 ± 7.7

31.7 ± 10.5

27.4 ± 9.8

0.478

0.681

0.135

0.881

Sulphate (mmol/24 h)

20.5 ± 6.5

20.7 ± 6.7

22.2 ± 5.9

23.4 ± 5.7

20.6 ± 5.2

0.881

0.218

0.161

0.852

Creatinine (mmol/24 h)

12.43 ± 3.50

13.46 ± 4.87

13.19 ± 4.28

13.27 ± 4.22

12.53 ± 3.97

0.232

0.563

0.279

0.940

Uric acid (mmol/24 h)

3.10 ± 0.90

3.27 ± 1.01

3.16 ± 0.74

3.35 ± 0.73

3.16 ± 0.89

0.305

0.681

0.370

0.695

Oxalate (mmol/24 h)

0.354 ± 0.097

0.542 ± 0.163

0.563 ± 0.183

0.638 ±0.197

0.371 ± 0.108

< 0.001

0.563

0.052

0.455

Citrate (mmol/24 h)

3.662 ± 1.567

3.553 ± 1.123

3.640 ± 1.517

3.969 ± 1.461

3.444 ± 1.233

0.526

0.970

0.021

0.279

RS CaOx

3.211 ± 1.672

4.398 ± 2.317

4.867 ± 2.921

5.111 ± 2.973

3.647 ± 2.151

0.004

0.550

0.108

0.332