Figure 4From: Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancerPXN promotes cell proliferation and colony formation in gastric cancer cells. A, PXN protein level is elevated after over-expression of PXN in AGS cells and reduced after knockdown of PXN in SGC7901 cells. B and C, Ectopic expression of PXN promotes cell proliferation in AGS cells (P = 0.017) whereas knockdown of PXN inhibits cell proliferation in SGC7901 cells as determined by MTT assays (P = 0.019). D and E, Ectopic expression of PXN stimulates colony formation in AGS cells (P = 0.026). F and G, Knockdown of PXN expression inhibits colony formation in SGC7901 cells (P = 0.011).Back to article page