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Table 4 Association between the percentage of surface receptors and cytotoxic granules positive NK cells and the clinicopathological features of gastric cancer

From: Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer

Gastric cancer
  NO. of patients NKG2D NKp30 NKp46 Perforin KIR3DL1
   % P % P % P % P % P
Histological grade  
Well/Moderately 12 89.0 ± 3.0 < 0.01 T 45.1 ± 24.4 < 0.05 U 56.3 ± 28.7 ns U 88.5 ± 7.6 < 0.05 U 15.3 ± 5.9 ns U
Poorly 19 86.2 ± 2.5   31.2 ± 17.7   46.2 ± 30.1   76.5 ± 17.4   20.5 ± 14.3  
Depth of invasion *            
Tis/T1/T2/T3 10 87.8 ± 3.2 ns T 48.0 ± 24.3 < 0.05 T 54.2 ± 29.1 ns U 85.5 ± 10.0 ns U 21.4 ± 12.7 ns U
T4 21 87.0 ± 2.9   31.1 ± 17.8   48.1 ± 29.1   79.1 ± 17.3   17.2 ± 11.6  
Lymph node metastasis            
Absent 11 89.3 ± 2.8 < 0.01 T 48.2 ± 22.7 < 0.05 T 57.6 ± 29.3 ns U 88.5 ± 8.1 < 0.05 U 15.1 ± 5.7 ns U
Present 20 86.1 ± 2.5   30.1 ± 17.9   46.0 ± 29.5   77.1 ± 17.1   20.4 ± 14.0  
Blood vessel invasion            
Absent 17 88.3 ± 3.0 < 0.05 T 38.0 ± 23.8 ns T 49.0 ± 29.6 ns U 84.5 ± 12.0 ns U 18.3 ± 10.8 ns U
Present 14 85.9 ± 2.5   34.8 ± 18.4   51.4 ± 30.5   77.1 ± 18.5   18.8 ± 13.6  
  1. *According to 2010 American Joint Committee on Cancer (AJCC), Tis, T1, T2, or T3 gastric cancer invades inside of gastric serosa; T4 gastric cancer invades outside of gastric serosa or adjacent organs. U represented Mann–Whitney U-tests and T represented independent t-tests. Data were expressed as means ± standard deviations (Mean ± SD).