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Table 3 Multivariate Cox regression hazard model for time to recurrence using a forward conditional selection method

From: Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

Prognostic indices model (n) HR 95% CI P value
Grade 1 and 2 1   
Grade 3 and 4 3.4 1.9-6.1 <0.001*
No capsular invasion present 1   
Capsular invasion present 5.4 3.0-10.0 <0.001*
Cav-1 and p-ERK1/2 covariate negative 1   
Cav-1 and p-ERK1/2 covariate positive 4.2 2.3-7.5 <0.001*
  1. Covariates used include: tumour grade, stage, size, capsular invasion, vascular invasion, Cav-1 and p-ERK1/2. The covariates of size, stage and vascular invasion are rejected as not influential in the model by the selection method.
  2. CI = 95% confidence limit, HR = Hazard Ratio * denotes significance P < 0.001.