Figure 2From: Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individualsReceiver operating characteristic (ROC) curve modeling the probability of colorectal cancer detection by CEA, TFRC and CA242. Data from colorectal cancer stage TNM I-II versus matched controls were included in the statistical calculation (n = 72). The x axis is 1-specificity and the y axis is sensitivity. The red line represents the combination of all three markers with maximum sensitivity and specificity of 53% and 90%, respectively. The area under the ROC curve (AUC) signifies the accuracy of the three combined biomarkers for distinguishing colorectal cancers (TNM I-II). The area under the curve was 0.861. The dotted black line represents the point of 90% specificity.Back to article page