Figure 4

Notch1 signaling inhibits mitochondrial mPTP opening in H9c2 cells exposed to ischemia. A, Measurement of ΔΨm in different groups of H9c2 cells. B, Measurement of ROS accumulation in different groups of H9c2 cells. Data were presented as mean±SD, n=3. Mock1 indicated cells infected with empty vector, Mock2 indicated cells infected with vector containing nonspecfic sequences. ▲P>0.05, *P<0.05, **P<0.01.