Table 1 Examples of effect formulas

m

Unscaled (e.g. occupancy, %)

%

m - m_bl

Change from baseline (raw)

Same unit as endpoint

m - m_ctrl

Change from control (raw)

Same unit as endpoint

100*((m -m_bl) / m_bl)

Change from baseline (%)

%

100*((m - m_ctrl) / (m_ctrl)

Change from control (%)

%

100*(N_sbj,grp/N_grp – N_sbj,ctrl /N_ctrl)

Diff in % Event (percentage points)

% (percentage points)