Table 3 Methylation patterns of the PTPRO genes in primary tumors, plasma samples from 24 breast cancer patients with Clinicopathological parameters

1

●

●

+

-

-

52

2

2

1

0

2

●

●

+

-

-

49

2

2

0

0

3

●

●

+

-

-

41

2

3

1

0

4

●

●

-

-

-

41

3

2

0

0

5

●

●

-

+

+

89

3

4

x

0

6

●

●

-

+

-

58

3

4

2

0

7

●

●

-

+

-

57

2

4

2

0

8

●

●

-

+

-

57

1

2

0

0

9

●

●

-

+

-

54

2

2

0

0

10

●

●

-

+

+

30

3

3

3

0

11

●

●

-

-

-

48

1

4

2

0

12

●

○

+

+

+

42

3

4

2

0

13

●

○

+

-

-

52

2

2

0

0

14

●

○

+

+

+

45

2

4

2

0

15

●

○

-

+

+

57

2

2

1

0

16

●

○

-

+

-

62

2

2

2

0

17

●

○

-

+

+

46

2

4

3

0

18

●

○

-

+

+

60

3

2

2

0

19

○

○

+

+

-

42

1

2

1

0

20

○

○

+

-

-

61

3

3

0

0

21

○

○

-

+

-

36

2

3

3

0

22

○

○

-

+

+

50

1

1

0

0

23

○

○

-

+

-

54

3

3

0

0

24

○

○

-

+

-

54

2

1

0

0

Methylation ratio (%)

18/24 (75.0)

11/24 (45.8)